TAF1B

TATA box-binding protein-associated factor RNA polymerase I subunit B; Isoform 2 of TATA box-binding protein-associated factor RNA polymerase I subunit B

Component of RNA polymerase I core factor complex that acts as a GTF2B/TFIIB-like factor and plays a key role in multiple steps during transcription initiation such as pre-initiation complex (PIC) assembly and postpolymerase recruitment events in polymerase I (Pol I) transcription. Binds rDNA promoters and plays a role in Pol I recruitment as a component of the SL1/TIF-IB complex and, possibly, directly through its interaction with RRN3.

    Matrix Type

    • Tissue/Cells

    Gene Symbol

    • TAF1B

    UniProt ID

    • Q53T94

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