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TAF1A

TATA box-binding protein-associated factor RNA polymerase I subunit A; Isoform 2 of TATA box-binding protein-associated factor RNA polymerase I subunit A

Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (pre-initiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits.

    Matrix Type

    • Tissue/Cells

    Gene Symbol

    • TAF1A

    UniProt ID

    • Q15573
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