Plasma membrane t-SNARE that mediates docking of transport vesicles (By similarity). Necessary for the translocation of SLC2A4 from intracellular vesicles to the plasma membrane (By similarity). In neurons, recruited at neurite tips to membrane domains rich in the phospholipid 1-oleoyl-2-palmitoyl-PC (OPPC) which promotes neurite tip surface expression of the dopamine transporter SLC6A3/DAT by facilitating fusion of SLC6A3-containing transport vesicles with the plasma membrane (By similarity). Together with STXB3 and VAMP2, may also play a role in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes and in docking of synaptic vesicles at presynaptic active zones (By similarity).

Matrix Type

  • Plasma
  • Tissue/Cells

Gene Symbol

  • STX4

UniProt ID

  • Q12846

Request the STX4 Assay

Tell us a little more about your study so we can optimize the assay for your specific needs.

"*" indicates required fields

This field is for validation purposes and should be left unchanged.