STEEP

Isoform 2 of STING ER exit protein;STING ER exit protein; Isoform 3 of STING ER exit protein

Molecular adapter that stimulates membrane curvature formation and subsequent endoplasmic reticulum exit site (ERES) establishment by recruiting PI3K complex I, leading to COPII vesicle-mediated transport (PubMed:32690950). Promotes endoplasmic reticulum (ER) exit of cGAMP-activated STING1 oligomers (PubMed:32690950, PubMed:37832545).

Matrix Type

Tissue/Cells

Gene Symbol

STEEP1

UniProt ID

Q9H5V9
Q9H5V9-3

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STEEP

Isoform 2 of STING ER exit protein;STING ER exit protein; Isoform 3 of STING ER exit protein

Matrix Type

Gene Symbol

UniProt ID

Request the STEEP Assay

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