May be involved in the regulation of serine proteinases present in the brain or extravasated from the blood (By similarity). Inhibitor of cathepsin G, kallikrein-8 and thrombin. May play an important role in the inner ear in the protection against leakage of lysosomal content during stress and loss of this protection results in cell death and sensorineural hearing loss.

Matrix Type

  • Plasma
  • Tissue/Cells

Gene Symbol

  • SERPINB6

UniProt ID

  • P35237

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