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SP140

Nuclear body protein SP140; Isoform 5 of Nuclear body protein SP140; Isoform 6 of Nuclear body protein SP140; Isoform Sp140 of Nuclear body protein SP140

Component of the nuclear body, also known as nuclear domain 10, PML oncogenic domain, and KR body (PubMed:8910577). May be involved in the pathogenesis of acute promyelocytic leukemia and viral infection (PubMed:8910577). May play a role in chromatin-mediated regulation of gene expression although it does not bind to histone H3 tails (PubMed:24267382).

    Matrix Type

    • Tissue/Cells

    Gene Symbol

    • SP140

    UniProt ID

    • Q13342
    • Q13342-5
    • Q13342-6
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