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SIMC1

Isoform 5 of SUMO-interacting motif-containing protein 1;SUMO-interacting motif-containing protein 1

Plays a role in SMC5-SMC6 complex recruitment for viral restriction. Forms a complex with SLF2 and this complex is required to recruit SMC5-SMC6 complex to PML nuclear bodies and sites of viral replication. ; [Isoform 1]: Inhibits the protease activity of CAPN3. ; [Isoform 5]: Inhibits the protease activity of CAPN3.

    Matrix Type

    • Tissue/Cells

    Gene Symbol

    • SIMC1

    UniProt ID

    • Q8NDZ2
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