SIA10

Type 2 lactosamine alpha-2,3-sialyltransferase; Isoform 2 of Type 2 lactosamine alpha-2,3-sialyltransferase;Type 2 lactosamine alpha-2,3-sialyltransferase

Involved in the synthesis of sialyl-paragloboside, a precursor of sialyl-Lewis X determinant. Has a alpha-2,3-sialyltransferase activity toward Gal-beta1,4-GlcNAc structure on glycoproteins and glycolipids. Has a restricted substrate specificity, it utilizes Gal-beta1,4-GlcNAc on glycoproteins, and neolactotetraosylceramide and neolactohexaosylceramide, but not lactotetraosylceramide, lactosylceramide or asialo-GM1.

Matrix Type

  • Plasma
  • Tissue/Cells

Gene Symbol

  • ST3GAL6

UniProt ID

  • Q9Y274

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