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SHKB1

SH3KBP1-binding protein 1

Inhibits CBL-SH3KBP1 complex mediated down-regulation of EGFR signaling by sequestration of SH3KBP1. Binds to SH3KBP1 and prevents its interaction with CBL and inhibits translocation of SH3KBP1 to EGFR containing vesicles upon EGF stimulation.

Associated with:

Matrix Type

  • Tissue/Cells

Gene Symbol

  • SHKBP1

UniProt ID

  • Q8TBC3
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