Restriction factor required to restrict infectivity of lentiviruses, such as HIV-1: acts by inhibiting an early step of viral infection. Impairs the penetration of the viral particle into the cytoplasm (PubMed:26416733, PubMed:26416734).

Associated with:

Matrix Type

  • Tissue/Cells

Gene Symbol

  • SERINC3

UniProt ID

  • Q13530

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