SAE2

SUMO-activating enzyme subunit 2

The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.

Matrix Type

Tissue/Cells

Gene Symbol

UBA2

UniProt ID

Q9UBT2

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SAE2

SUMO-activating enzyme subunit 2

Associated with:

Matrix Type

Gene Symbol

UniProt ID

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