Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5′ splice-site and the subsequent assembly of the spliceosome (PubMed:19325628, PubMed:25555158). SNRNP70 binds to the loop I region of U1-snRNA (PubMed:19325628, PubMed:2467746, PubMed:25555158). ; [Isoform 3]: Truncated isoforms that lack the RRM domain cannot bind U1-snRNA. ; [Isoform 4]: Truncated isoforms that lack the RRM domain cannot bind U1-snRNA.

    Matrix Type

    • Tissue/Cells

    Gene Symbol

    • SNRNP70

    UniProt ID

    • P08621

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