Zinc phosphodiesterase, which displays some tRNA 3′-processing endonuclease activity (PubMed:12711671, PubMed:32075755). Specifically involved in tRNA repair: acts downstream of the ribosome-associated quality control (RQC) pathway by removing a 2′,3′-cyclic phosphate from tRNAs following cleavage by ANKZF1 (PubMed:32075755). tRNAs are then processed by TRNT1 (PubMed:32075755).

Matrix Type

  • Tissue/Cells

Gene Symbol

  • ELAC1

UniProt ID

  • Q9H777

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