RHG09

Isoform 3 of Rho GTPase-activating protein 9; Isoform 5 of Rho GTPase-activating protein 9; Isoform 2 of Rho GTPase-activating protein 9; Isoform 4 of Rho GTPase-activating protein 9;Rho GTPase-activating protein 9

GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has a substantial GAP activity toward CDC42 and RAC1 and less toward RHOA. Has a role in regulating adhesion of hematopoietic cells to the extracellular matrix. Binds phosphoinositides, and has the highest affinity for phosphatidylinositol 3,4,5-trisphosphate, followed by phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol 4,5-bisphosphate.

    Matrix Type

    • Tissue/Cells

    Gene Symbol

    • ARHGAP9

    UniProt ID

    • Q9BRR9
    • Q9BRR9-3
    • Q9BRR9-4
    • Q9BRR9-5

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