RFOX2

Isoform 6 of RNA binding protein fox-1 homolog 2; Isoform 8 of RNA binding protein fox-1 homolog 2

RNA-binding protein that regulates alternative splicing events by binding to 5′-UGCAUGU-3′ elements. Prevents binding of U2AF2 to the 3′-splice site. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis (By similarity). RNA-binding protein that seems to act as a coregulatory factor of ER-alpha. Together with RNA binding proteins RBPMS and MBNL1/2, activates vascular smooth muscle cells alternative splicing events (PubMed:37548402).

Matrix Type

  • Tissue/Cells

Gene Symbol

  • RBFOX2

UniProt ID

  • O43251-6

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