REPS2

RalBP1-associated Eps domain-containing protein 2;RalBP1-associated Eps domain-containing protein 2; Isoform 2 of RalBP1-associated Eps domain-containing protein 2

Involved in ligand-dependent receptor mediated endocytosis of the EGF and insulin receptors as part of the Ral signaling pathway (PubMed:10393179, PubMed:12771942, PubMed:9422736). By controlling growth factor receptors endocytosis may regulate cell survival (PubMed:12771942). Through ASAP1 may regulate cell adhesion and migration (PubMed:12149250).

Associated with:

Matrix Type

  • Plasma
  • Tissue/Cells

Gene Symbol

  • REPS2

UniProt ID

  • Q8NFH8

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