PROM1

Isoform 2 of Prominin-1; Isoform 4 of Prominin-1; Isoform 7 of Prominin-1; Isoform 6 of Prominin-1;Prominin-1; Isoform 3 of Prominin-1; Isoform 5 of Prominin-1

May play a role in cell differentiation, proliferation and apoptosis (PubMed:24556617). Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner (PubMed:20818439).

    Matrix Type

    • Tissue/Cells

    Gene Symbol

    • PROM1

    UniProt ID

    • O43490
    • O43490-3
    • O43490-4
    • O43490-5
    • O43490-6
    • O43490-7

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