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PORCN

Protein-serine O-palmitoleoyltransferase porcupine; Isoform 5 of Protein-serine O-palmitoleoyltransferase porcupine; Isoform 2 of Protein-serine O-palmitoleoyltransferase porcupine; Isoform 3 of Protein-serine O-palmitoleoyltransferase porcupine; Isoform 4 of Protein-serine O-palmitoleoyltransferase porcupine

Protein-serine O-palmitoleoyltransferase that acts as a key regulator of the Wnt signaling pathway by mediating the attachment of palmitoleate, a 16-carbon monounsaturated fatty acid (C16:1(9Z)), to Wnt proteins. Serine palmitoleoylation of WNT proteins is required for efficient binding to frizzled receptors.

    Matrix Type

    • Tissue/Cells

    Gene Symbol

    • PORCN

    UniProt ID

    • Q9H237
    • Q9H237-3
    • Q9H237-4
    • Q9H237-5
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