POGZ

Isoform 3 of Pogo transposable element with ZNF domain; Isoform 5 of Pogo transposable element with ZNF domain; Isoform 2 of Pogo transposable element with ZNF domain;Pogo transposable element with ZNF domain

Plays a role in mitotic cell cycle progression and is involved in kinetochore assembly and mitotic sister chromatid cohesion. Probably through its association with CBX5 plays a role in mitotic chromosome segregation by regulating aurora kinase B/AURKB activation and AURKB and CBX5 dissociation from chromosome arms (PubMed:20562864). Promotes the repair of DNA double-strand breaks through the homologous recombination pathway (PubMed:26721387).

Associated with:

Matrix Type

  • Tissue/Cells

Gene Symbol

  • POGZ

UniProt ID

  • Q7Z3K3
  • Q7Z3K3-3
  • Q7Z3K3-5

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