POC1B

Isoform 2 of POC1 centriolar protein homolog B;POC1 centriolar protein homolog B

Plays an important role in centriole assembly and/or stability and ciliogenesis (PubMed:20008567, PubMed:32060285). Involved in early steps of centriole duplication, as well as in the later steps of centriole length control (PubMed:19109428). Acts in concert with POC1A to ensure centriole integrity and proper mitotic spindle formation (PubMed:32060285). Required for primary cilia formation, ciliary length and also cell proliferation (PubMed:23015594). Required for retinal integrity (PubMed:25044745).

    Matrix Type

    • Tissue/Cells

    Gene Symbol

    • POC1B

    UniProt ID

    • Q8TC44

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