PLCC

1-acyl-sn-glycerol-3-phosphate acyltransferase gamma;1-acyl-sn-glycerol-3-phosphate acyltransferase gamma; Isoform 2 of 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma; Isoform 3 of 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma

Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (PubMed:21173190). Acts on LPA containing saturated or unsaturated fatty acids C16:0-C20:4 at the sn-1 position using C18:1, C20:4 or C18:2-CoA as the acyl donor (PubMed:21173190). Also acts on lysophosphatidylcholine, lysophosphatidylinositol and lysophosphatidylserine using C18:1 or C20:4-CoA (PubMed:21173190). Has a preference for arachidonoyl-CoA as a donor (By similarity). Has also a modest lysophosphatidylinositol acyltransferase (LPIAT) activity, converts lysophosphatidylinositol (LPI) into phosphatidylinositol (By similarity).

Matrix Type

  • Plasma
  • Tissue/Cells

Gene Symbol

  • AGPAT3

UniProt ID

  • Q9NRZ7
  • Q9NRZ7-3

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