Acts as a positive regulator of hedgehog signaling and regulates ciliary function. ; [Isoform 1]: Functions as a co-chaperone for CCT in the assembly of heterotrimeric G protein complexes, facilitates the assembly of both Gbeta-Ggamma and RGS-Gbeta5 heterodimers.; [Isoform 2]: Acts as a negative regulator of heterotrimeric G proteins assembly by trapping the preloaded G beta subunits inside the CCT chaperonin.

    Matrix Type

    • Tissue/Cells

    Gene Symbol

    • PDCL

    UniProt ID

    • Q13371

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