Neurotrophic protein; induces extensive neuronal differentiation in retinoblastoma cells. Potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.

Associated with:

Matrix Type

  • Plasma
  • Tissue/Cells

Gene Symbol

  • SERPINF1

UniProt ID

  • P36955

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