PDP2

[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial

Mitochondrial enzyme that catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex (PDC), thereby stimulating the conversion of pyruvate into acetyl-CoA (By similarity). Acts as a crucial regulator of T cell metabolism and function, with a particular focus on T-helper Th17 (By similarity).

Matrix Type

  • Tissue/Cells

Gene Symbol

  • PDP2

UniProt ID

  • Q9P2J9

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