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PCMD2

Isoform 3 of Protein-L-isoaspartate O-methyltransferase domain-containing protein 2;Protein-L-isoaspartate O-methyltransferase domain-containing protein 2; Isoform 2 of Protein-L-isoaspartate O-methyltransferase domain-containing protein 2

May act as a substrate recognition component of an ECS (Elongin BC-CUL5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. May bind to the methyltransferase cofactor S-adenosylmethionine (AdoMet) via the N-terminal AdoMet binding motif, but probably does not display methyltransferase activity.

    Matrix Type

    • Tissue/Cells

    Gene Symbol

    • PCMTD2

    UniProt ID

    • Q9NV79
    • Q9NV79-3
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