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NUBP2

Cytosolic Fe-S cluster assembly factor NUBP2

Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Negatively regulates cilium formation and structure.

    Matrix Type

    • Tissue/Cells

    Gene Symbol

    • NUBP2

    UniProt ID

    • Q9Y5Y2
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