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NSD3

Histone-lysine N-methyltransferase NSD3; Isoform 5 of Histone-lysine N-methyltransferase NSD3; Isoform 2 of Histone-lysine N-methyltransferase NSD3; Isoform 4 of Histone-lysine N-methyltransferase NSD3

Histone methyltransferase. Preferentially dimethylates ‘Lys-4’ and ‘Lys-27’ of histone H3 forming H3K2me2 and H3K27me2. H3 ‘Lys-4’ methylation represents a specific tag for epigenetic transcriptional activation, while ‘Lys-27’ is a mark for transcriptional repression.

    Matrix Type

    • Tissue/Cells

    Gene Symbol

    • NSD3

    UniProt ID

    • Q9BZ95
    • Q9BZ95-4
    • Q9BZ95-5
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