NIN

Isoform 7 of Ninein; Isoform 3 of Ninein; Isoform 2 of Ninein; Isoform 4 of Ninein;Ninein

Centrosomal protein required in the positioning and anchorage of the microtubule minus-end in epithelial cells (PubMed:15190203, PubMed:23386061). May also act as a centrosome maturation factor (PubMed:11956314). May play a role in microtubule nucleation, by recruiting the gamma-tubulin ring complex to the centrosome (PubMed:15190203). Overexpression does not perturb nucleation or elongation of microtubules but suppresses release of microtubules (PubMed:15190203). Required for centriole organization and microtubule anchoring at the mother centriole (PubMed:23386061).

Matrix Type

  • Tissue/Cells

Gene Symbol

  • NIN

UniProt ID

  • Q8N4C6
  • Q8N4C6-2
  • Q8N4C6-4
  • Q8N4C6-7

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