NCKP1

Nck-associated protein 1;Nck-associated protein 1; Isoform 2 of Nck-associated protein 1

Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes.

Matrix Type

  • Plasma
  • Tissue/Cells

Gene Symbol

  • NCKAP1

UniProt ID

  • Q9Y2A7

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