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MET17

Isoform 2 of Methyltransferase-like protein 17, mitochondrial; Isoform 3 of Methyltransferase-like protein 17, mitochondrial;Methyltransferase-like protein 17, mitochondrial

Mitochondrial ribosome (mitoribosome) assembly factor (PubMed:36482135, PubMed:38199006). Binds at the interface of the head and body domains of the mitochondrial small ribosomal subunit (mt-SSU), occluding the mRNA channel and preventing compaction of the head domain towards the body (PubMed:36482135). Probable inactive methyltransferase: retains the characteristic folding and ability to bind S-adenosyl-L-methionine, but it probably lost its methyltransferase activity (PubMed:38234605).

    Matrix Type

    • Tissue/Cells

    Gene Symbol

    • METTL17

    UniProt ID

    • Q9H7H0
    • Q9H7H0-3
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