Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down-regulation of EGF receptor.

Matrix Type

  • Tissue/Cells

Gene Symbol

  • MVB12A

UniProt ID

  • Q96EY5

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