MAST2

Microtubule-associated serine/threonine-protein kinase 2; Isoform 2 of Microtubule-associated serine/threonine-protein kinase 2

Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins. Functions in a multi-protein complex in spermatid maturation. Regulates lipopolysaccharide-induced IL-12 synthesis in macrophages by forming a complex with TRAF6, resulting in the inhibition of TRAF6 NF-kappa-B activation (By similarity).

Matrix Type

  • Tissue/Cells

Gene Symbol

  • MAST2

UniProt ID

  • Q6P0Q8

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