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LRRF2

Leucine-rich repeat flightless-interacting protein 2;Isoform 4 of Leucine-rich repeat flightless-interacting protein 2;Isoform 2 of Leucine-rich repeat flightless-interacting protein 2; Isoform 4 of Leucine-rich repeat flightless-interacting protein 2

May function as activator of the canonical Wnt signaling pathway, in association with DVL3, upstream of CTNNB1/beta-catenin. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding.

    Matrix Type

    • Plasma
    • Tissue/Cells

    Gene Symbol

    • LRRFIP2

    UniProt ID

    • Q9Y608
    • Q9Y608-2
    • Q9Y608-4
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