LRC15

Leucine-rich repeat-containing protein 15;Leucine-rich repeat-containing protein 15; Isoform 2 of Leucine-rich repeat-containing protein 15

(Microbial infection) Modulates the ability of SARS-CoV-2 to infect host cells through interaction with the spike protein (PubMed:36228039, PubMed:36735681, PubMed:36757924). Does not act as a SARS-CoV-2 entry receptor but sequesters virions and antagonizes in trans SARS-CoV-2 infection of ACE2(+) cells when expressed on nearby cells (PubMed:36228039, PubMed:36757924).

Matrix Type

  • Plasma
  • Tissue/Cells

Gene Symbol

  • LRRC15

UniProt ID

  • Q8TF66

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