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LIRB3

Isoform 2 of Leukocyte immunoglobulin-like receptor subfamily B member 3; Isoform 3 of Leukocyte immunoglobulin-like receptor subfamily B member 3;Leukocyte immunoglobulin-like receptor subfamily B member 3

May act as receptor for class I MHC antigens. Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. Down-regulates antigen-induced B-cell activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitor motifs (ITIM).

Associated with:

Matrix Type

  • Tissue/Cells

Gene Symbol

  • LILRB3

UniProt ID

  • O75022
  • O75022-3
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