May act as transcription activator that binds DNA elements with the sequence 5′-CCCTATCGATCGATCTCTACCT-3′ (By similarity). Repressor of ligand-dependent transcription activation by target nuclear receptors. Repressor of ligand-dependent transcription activation by ESR1, ESR2, NR3C1, PGR, RARA, RARB, RARG, RXRA and VDR.
