KLKB1

Plasma kallikrein

Participates in the surface-dependent activation of blood coagulation. Activates, in a reciprocal reaction, coagulation factor XII/F12 after binding to negatively charged surfaces. Releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin.

Associated with:

Acute Kidney Injury
Alanine Transaminase
Albumin
Alkaline Phosphatase
Anemia
Angina Pectoris
Apolipoprotein A
Apolipoprotein B
Asthma
Atrial Fibrillation
Basal Cell Skin Cancer
Basal Metabolic Rate
Basophils
Bilirubin
BMI
Breast Cancer
C Reactive Protein
Calcium
Calcium Albumin Ratio
Cancer
Chronic Ischaemic Heart Disease
Chronik Kidney Diesase
Creatinine
Depression
Diastolic Blood Pressure
Direct Bilirubin
Disorder Of Lipoprotein Metabolism
Epilepsy
Erythrocyte Sedimentation Rate
Estimated Glomerular Filtration Rate
Ferritin
Folate
FT3 FT4 Ratio
Gallstones
Gamma Glutamyltransferase
Glucose
Gout
Granulocytes
HbA1c
Heart Failure
Heartrate
Height
Hemoglobin
Hepatic Failure
High Density Lipoprotein Cholesterol
Hip Bone Mineral Density
Hip Osteoarthritis
Hypertension
Hypotension
IgA
IGF1
Insomnia
Iron
Kidney Cancer
Kidney Failure
Knee Osteoarthritis
Lactate Dehydrogenase
Leukocytes
Lipoprotein A
Liver Cirrhosis
Low Density Lipoprotein Cholesterol
Lymphocytes
Metabolic Syndrome
Monocytes
Myocardial Infarction
Neutrophils
Oesophageal Varices
Phneumonia
Phosphate
Plasma Prothrombin Time
Platelet
Prostate Cancer
Red Blood Cell Count
Reticulocytes
Rheumatoid Arthritis
Severe Obesity (BMI > 35)
Sleep Disorders
Systolic Blood Pressure
Testosterone
Thyroid FT3
Total Bilirubin
Total Cholesterol
Total Fat
Total Lean Muscle
Transferrin Saturation
Triglyceride
Type 2 Diabetes
Urea
Uric Acid
Urine Glucose
Urine Protein
Vitamin D
Waist Circumference
Waist Hip Ratio
Weight
White Blood Cell
Whole Body Fat
Complement
Coagulation
Inflammatory Response

Matrix Type

Plasma
Tissue/Cells

Gene Symbol

KLKB1

UniProt ID

P03952

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KLKB1

Plasma kallikrein

Associated with:

Matrix Type

Gene Symbol

UniProt ID

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