KIF2C

Kinesin-like protein KIF2C;Isoform 2 of Kinesin-like protein KIF2C

In complex with KIF18B, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells (PubMed:21820309). Regulates the turnover of microtubules at the kinetochore and functions in chromosome segregation during mitosis (PubMed:19060894). Plays a role in chromosome congression and is required for the lateral to end-on conversion of the chromosome-microtubule attachment (PubMed:23891108).

Matrix Type

  • Tissue/Cells

Gene Symbol

  • KIF2C

UniProt ID

  • Q99661
  • Q99661-2

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