ISK5

Isoform long of Serine protease inhibitor Kazal-type 5;Serine protease inhibitor Kazal-type 5; Isoform short of Serine protease inhibitor Kazal-type 5

Serine protease inhibitor, probably important for the anti-inflammatory and/or antimicrobial protection of mucous epithelia. Contribute to the integrity and protective barrier function of the skin by regulating the activity of defense-activating and desquamation-involved proteases. Inhibits KLK5, it’s major target, in a pH-dependent manner. Inhibits KLK7, KLK14 CASP14, and trypsin.

Associated with:

Matrix Type

  • Tissue/Cells

Gene Symbol

  • SPINK5

UniProt ID

  • Q9NQ38
  • Q9NQ38-3

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