IF122

Isoform 9 of Intraflagellar transport protein 122 homolog;Isoform 3 of Intraflagellar transport protein 122 homolog; Isoform 6 of Intraflagellar transport protein 122 homolog; Isoform 4 of Intraflagellar transport protein 122 homolog; Isoform 10 of Intraflagellar transport protein 122 homolog; Isoform 6 of Intraflagellar transport protein 122 homolog; Isoform 5 of Intraflagellar transport protein 122 homolog;Intraflagellar transport protein 122 homolog; Isoform 4 of Intraflagellar transport protein 122 homolog; Isoform 3 of Intraflagellar transport protein 122 homolog

As a component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs), it is required in ciliogenesis and ciliary protein trafficking (PubMed:27932497, PubMed:29220510). Involved in cilia formation during neuronal patterning. Acts as a negative regulator of Shh signaling. Required to recruit TULP3 to primary cilia (By similarity).

    Matrix Type

    • Tissue/Cells

    Gene Symbol

    • IFT122

    UniProt ID

    • Q9HBG6
    • Q9HBG6-3
    • Q9HBG6-4
    • Q9HBG6-5
    • Q9HBG6-6
    • Q9HBG6-9

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