HGF

Isoform 4 of Hepatocyte growth factor; Isoform 3 of Hepatocyte growth factor; Isoform 5 of Hepatocyte growth factor; Isoform 6 of Hepatocyte growth factor;Hepatocyte growth factor; Isoform 2 of Hepatocyte growth factor

Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types (PubMed:20624990). Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization (PubMed:15167892, PubMed:20977675). Activates MAPK signaling following TMPRSS13 cleavage and activation (PubMed:20977675).

Associated with:

Matrix Type

  • Tissue/Cells

Gene Symbol

  • HGF

UniProt ID

  • P14210
  • P14210-3
  • P14210-4
  • P14210-5
  • P14210-6

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