HERP1

Isoform 2 of Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein;Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein

Component of the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins (PubMed:16289116, PubMed:28827405). Could enhance presenilin-mediated amyloid-beta protein 40 generation. Binds to ubiquilins and this interaction is required for efficient degradation of CD3D via the ERAD pathway (PubMed:18307982).

Associated with:

Unfolded Protein Response

Matrix Type

Tissue/Cells

Gene Symbol

HERPUD1

UniProt ID

Q15011

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HERP1

Isoform 2 of Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein;Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein

Associated with:

Matrix Type

Gene Symbol

UniProt ID

Request the HERP1 Assay

SERVICES

APPLICATIONS

PARTNERING

RESOURCES

ABOUT