Can degrade highly structured RNAs through its concerted ATP-dependent RNA helicase and 3′ to 5′ exoribonuclease activities (PubMed:37602378). Shows a strong preference for pyrimidine over purine residues for its nuclease activity (PubMed:37602378). Acts as a transcriptional coactivator for a number of nuclear receptors including PPARA, PPARG, THRA, THRB and RXRA (PubMed:16239304, PubMed:23525231).