HELLS

Lymphoid-specific helicase; Isoform 2 of Lymphoid-specific helicase

Plays an essential role in normal development and survival. Involved in regulation of the expansion or survival of lymphoid cells. Required for de novo or maintenance DNA methylation. May control silencing of the imprinted CDKN1C gene through DNA methylation. May play a role in formation and organization of heterochromatin, implying a functional role in the regulation of transcription and mitosis (By similarity).

Associated with:

Matrix Type

  • Tissue/Cells

Gene Symbol

  • HELLS

UniProt ID

  • Q9NRZ9

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