H6ST1

Heparan-sulfate 6-O-sulfotransferase 1; Isoform 2 of Heparan-sulfate 6-O-sulfotransferase 1

6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3′-phosphoadenosine 5′-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. Critical for normal neuronal development where it may play a role in neuron branching. May also play a role in limb development. May prefer iduronic acid.

Associated with:

Matrix Type

  • Tissue/Cells

Gene Symbol

  • HS6ST1

UniProt ID

  • O60243

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