Catalyzes the synthesis of cyclic GMP (cGMP) in rods and cones of photoreceptors. Plays an essential role in phototransduction, by mediating cGMP replenishment (PubMed:15123990, PubMed:21928830, PubMed:26100624, PubMed:30319355, PubMed:9600905). May also participate in the trafficking of membrane-asociated proteins to the photoreceptor outer segment membrane (By similarity).

Matrix Type

  • Tissue/Cells

Gene Symbol

  • GUCY2D

UniProt ID

  • Q02846

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