May play a role in intracellular immune modulation by activating NF-kappaB response and attenuating Toll-like-receptor response. ; (Microbial infection) Plays an essential function in adeno-associated virus (AAV) transduction across multiple serotypes except AAV5. May play a critical role in mediating the endosomal virus escape or in the AAV virions trafficking from endosomes to the nucleus.
