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GNPTA

N-acetylglucosamine-1-phosphotransferase subunits alpha/beta

Catalyzes the formation of mannose 6-phosphate (M6P) markers on high mannose type oligosaccharides in the Golgi apparatus. M6P residues are required to bind to the M6P receptors (MPR), which mediate the vesicular transport of lysosomal enzymes to the endosomal/prelysosomal compartment.

    Matrix Type

    • Tissue/Cells

    Gene Symbol

    • GNPTAB

    UniProt ID

    • Q3T906
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