FWCH1

Isoform 2 of FLYWCH-type zinc finger-containing protein 1; Isoform 3 of FLYWCH-type zinc finger-containing protein 1;FLYWCH-type zinc finger-containing protein 1

Transcription cofactor (PubMed:30097457). Negatively regulates transcription activation by catenin beta-1 CTNNB1, perhaps acting by competing with TCF4 for CTNNB1 binding (PubMed:30097457). May play a role in DNA-damage response signaling (PubMed:33924684). Binds specifically to DNA sequences at peri-centromeric chromatin loci.

    Matrix Type

    • Tissue/Cells

    Gene Symbol

    • FLYWCH1

    UniProt ID

    • Q4VC44
    • Q4VC44-3

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