Binds directly and specifically 1,2-Diacyl-sn-glycero-3-phospho-(1′-myo-inositol-3′,4′,5′-bisphosphate) (PIP3) leading to the recruitment of PIP3 to mitochondria and may play a role in the regulation of the platelet activation via AKT/GSK3B/cGMP signaling pathways (PubMed:29786068). May act as transcription factor that regulates SREBP1 (isoform SREBP-1C) expression in order to modulate triglyceride (TG) homeostasis in hepatocytes (PubMed:25855506, PubMed:29187281).

    Matrix Type

    • Plasma
    • Tissue/Cells

    Gene Symbol

    • FUNDC2

    UniProt ID

    • Q9BWH2

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